Research Laboratory “Multimodal Microscopy and Biosensor Technologies”

The Multimodal Microscopy and Biosensor Technologies Research Laboratory was established in 2026 as part of project BR28712227, “Development and Implementation of High-Tech Solutions for Monitoring, Treatment and Rational Use of Water Resources in the North Kazakhstan Region to Ensure Public Health.”

Laboratory objective: To develop and implement advanced methods for analyzing and monitoring the quality of water, biological fluids and the environment based on multisensor approaches, high-resolution microscopy and advanced sample preparation technologies, with a long-term perspective of enabling flow-through analysis of clinical samples.

Main objectives of the laboratory:

• Development and validation of next-generation biosensor systems, including electrochemical biosensors using molecularly imprinted polymers (MIPs) for the selective detection of toxicants (pesticides, heavy metals and bacterial toxins); potentiostatic and impedance sensors for the analysis of water from various sources and biological samples.
• Sample preparation and concentration: Development of filtering materials and adsorbents (e.g., cryogel-based materials) for the preliminary concentration of low-level contaminants; use of cryostats, freeze-drying and vacuum plasma cleaning for sample preparation prior to microscopy and electrochemical analysis.
• Microscopic and spectroscopic analysis: Application of fluorescence and confocal microscopy for the analysis of cells, microorganisms, plant and biological tissues; use of a scanning electron microscope for the morphological analysis of filters, soil samples, minerals and bacteria before and after purification and bioremediation processes.
• Physicochemical and thermodynamic studies of bioprocesses: Measurement of the heat effects of microorganism growth using an isothermal calorimeter to monitor bioremediation processes and control microbiological activity.
• Water quality analysis and nanoparticle monitoring: Determination of the size, charge and distribution of nanoparticles using the Zetasizer Lab; development of rapid methods for monitoring drinking, wastewater and surface water.
• Development of calibration and confirmatory analysis methodology: Use of high-performance liquid chromatography–mass spectrometry (HPLC-MS) as a confirmatory method for verifying biosensor data and developing calibration models.

Range of Services Offered by the Multimodal Microscopy and Biosensor Technologies Research Laboratory

Material and Technical Facilities of the Research Laboratory

Structure

Suleymenova Akmaral

PhD

Head of the Research Laboratory

+7 (7152) 493233, add.   
Building 2, 1st floor, Room 106A

Iklasova Kaynizhamal Esimseitovna

PHD

Research Scientist

+7 (7152) 493233, add. 
Building 2, 1st floor, Room 106A
keiklasova@ku.edu.kz

Semenyuk Vladislav Vladimirovich 

master

Senior Researcher

+7 (7152) 493233, add.  
Building 2, 1st floor, Room 106A
vvsemenyuk@ku.edu.kz

Muhammad Saqib Saif

Senior Researcher

+7 (7152) 493233, add.  
Building 2, 1st floor, Room 106A
 

Dr. Lokeswara Reddy 

Leading Researcher

+7 (7152) 493233, add.  
Building 2, 1st floor, Room 106A
lrsanivarapu@ku.edu.kz

Gadetskaya Anastasia Valeryevna

Research Scientist

+7 (7152) 493233, add.  
Building 2, 1st floor, Room 106A
avgadeckaya@ku.edu.kz

Kudryavtseva Polina 

Research Associate

+7 (7152) 493233, add. 
Building 2, 1st floor, Room 106A